Shibani Pati, MD, PhD
Professor (UCSF Departments of Lab Medicine and Surgery) (Director - Center for Research in Transfusion Medicine and Cell Therapies)
Dr. Pati is a translational vascular biologist. Her specific areas of investigation involve the use of stem cells, blood products and novel resuscitative modalities that can mitigate endothelial dysfunction, inflammation and coagulation disturbances in hemorrhage and trauma. Her lab also has research efforts aimed at understanding the mechanisms of vascular compromise in traumatic brain injury (TBI) and novel methods by which to mitigate it, with the intention of impacting patient outcomes. Her recent focus in TBI has been in studying the regenerative properties of novel blood products.
Callie Keane
[email protected]
Staff Research Associate I
Alpa Mahuvakar, PhD
[email protected]
Researcher (UCSF Dept. of Lab Medicine)
I am a Senior Researcher in the Department of Laboratory Medicine, in Dr. Shibani Pati’s laboratory. As a trained molecular and cell biologist, my research at UCSF has focused on neurotrauma, including spinal cord injury (SCI) and traumatic brain injury (TBI). My research goals have aimed to assess the effect of neuroinflammation on outcomes after trauma, specifically, aimed at vascular dysfunction and neurobehavior after injury. I have tested several cell-based as well as small molecule-based therapeutics with the goal of reducing secondary damage after the primary insult. Currently, I lead all the projects that evaluate the novel blood products in TBI and polytrauma models in the Pati lab.
Byron Miyazawa
[email protected]
Staff Research Associate III (UCSF Dept. of Lab Medicine)
With a background in coagulation and endothelial dysfunction, my research is focused on the application of cell therapies and novel blood products in massive trauma. More specifically, my goals are to study and assess the effects of therapy products such as stem cells, platelets, and extracellular vesicles on inflammation and vascular dysfunction. Primarily utilizing a wide array of in vitro assays, my work centers around endothelial permeability and function, leukocyte activation, and mediators of coagulation.
Allison Nair, MD
Associate Professor, Pediatrics